Mimotopes. Mimotopes are peptides that mimic the effects of specific B-cell epitopes in stimulating an immune response. Immunization with such mimotopes.
Mimotopes are molecules - often peptides - that are recognized by antibodies or T cells that were primed to recognize a different epitope. For antibody epitope.
Mimotope vaccines. Many microbial pathogens and tumour cells evade immune surveillance by possessing polysaccharides or carbohydrates on their surfaces;.
Cho HS, Mason K, Ramyar KX, Mimotope
al. Biological impediments to monoclonal antibody-based cancer immunotherapy. Langley KE, Egan KM, Barendt JM et al. However, this concept Mimotope
been extended to refer peptide mimic of all types of binding sites. Results are representative of an experiment performed twice.
Mimotope - deposit
Plasmid construction and random peptide libraries. Huang YX, Bao YL, Guo SY, et al. In the near future, mimotopes could be an alternative prophylactic, adjuvant and therapeutic strategy against allergy and cancer. Consequently, SIT with whole allergen extracts or recombinant proteins, respectively, will produce both types of anti-allergen IgG, anaphylactogenic and blocking antibodies. Immunogenic mimics, on the other hand, form molecular contacts with the selecting antibody similar to those that engage the antigen itself, and are therefore more likely to provoke antibodies that bind the antigen. Abstract Background Mimotopes are peptides mimicking protein, carbohydrates or lipid epitopes and can be generated by phage display technology.